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Nonetheless, there are differences in clinical efficacies of these drugs and some are also able to reduce body weight in obese patients, improve cardiovascular outcomes, and may have benefit for the treatment of neurodegenerative disorders (Brown et al., 2018

Until then, she urges people to be skeptical of marketing claims that aren't substantiated by clinical evidence

Author CB received lecture fees and served as a consultant for Takeda, MSD, Ferring, Abbvie, Galapagos and Janssen

While fat loss is desirable, losing muscle can negatively impact metabolism, strength, and overall health

doi:10.1056/NEJMoa1901118 14Armstrong MJ, Gaunt P, Aithal GP, et al

| DOI: 10.1001/jama.2025.14392 Copyright 2025 by the American Medical Association