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flank: p = 0.6482) (k) levels in mice bearing orthotopic (n = 11), flank (n = 4), or no Gclc WT tumors (n = 8)

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While others have utilized droplet microfluidics-based approaches to link the heavy and light chains from a single BCR and build natively paired scFv libraries, few of these previous efforts have bioinformatically and experimentally validated the degree of native pairing 16 and the composition of antigen-specific clones within these in vivo-derived repertoires 19

The findings showed that chronic (long-term) treatment with Tesofensine increased the expression of BDNF mRNA by 35% in the CA3 region of the hippocampus, and Arc mRNA by 65% in the CA1 region