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10.1016/j.arr.2022.101721 221 ShuklaM.WongchitratP.GovitrapongP
(ii) increased GABA production resulting in disruption of circuit functions 154,155
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The same mitogenic activity is the basis of long-term cancer concern, because IGF-1 signaling is one of the more well-documented growth pathways studied in tumor biology
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Long-Term Safety Questions While short-term safety data for tirzepatide is reassuring, the long-term implications of dual agonism remain incompletely understood
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