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Identification of the peptide-antibody fusion MEDI4166 Following expression, V19A and L26I variants showed the highest percentage of monomeric product post-protein A purification and the lowest aggregation after a 4 week 5 C incubation at the target concentration of 50 mg/mL (Supplementary Fig

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Efficacy and safety of liraglutide in patients with an ileal pouch-anal anastomosis and chronic high bowel frequency: a placebo-controlled, crossover, proof-of-concept study

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Continued research, cautious clinical integration, and clear differentiation between adult and pediatric data will be essential to ensuring safe and effective use of these agents in adolescent obesity care

Conclusions SGLT-2 inhibitors and GLP-1RA are superior to DPP-4 inhibitors in reducing the risk of most cardiorenal outcomes