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Additionally, ethical concerns arise regarding potential off-label use of GLP-1RAs in high-risk populations without sufficient safety data, particularly in individuals without comorbid metabolic disorders
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By slowing gastric emptying and increasing feelings of satiety, patients often experience reduced appetite and caloric intake, leading to significant weight loss over time
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Starting Weight Individuals with a higher initial body weight may experience greater absolute weight loss, although the percentage change may be similar
