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Experimental models include isolated perfused hearts (Langendorff), ex vivo working heart preparations, in vivo echocardiography with metabolic phenotyping, transgenic models affecting carnitine metabolism (OCTN2 knockout, CPT-I variants), and large animal models of myocardial infarction

It is also important to note that the titration schedule used in trials was designed specifically to minimise tolerability problems

A patient drawing the wrong volume because they applied their Wegovy mg number to syringe units at the wrong concentration can over- or under-dose by 2x or more