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Sinclair AJ, Burdon MA, Nightingale PG, Ball AK, Good P, Matthews TD, Jacks A, Lawden M, Clarke CE, Stewart PM, Walker EA, Tomlinson JW, Rauz S

Indeed, mitochondrial disorders often result in central nervous system (CNS) dysfunction, leading to developmental regression, learning disability, and various behavioral disturbances

Surprisingly, only a small fraction (8.6% up and 11% down) of the enriched pathways were in the immune system or infectious disease KEGG KO subclasses in the BRITE hierarchy (Table B S1 File)

Dynamic regulation of hypoxia-inducible factor-1 activity is essential for normal B cell development