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Frontiers in Pharmacology, 16 , 1572156

Its primary function is to directly neutralize harmful reactive oxygen species (ROS) and free radicals, preventing them from causing damage to cellular components like DNA, proteins, and lipids

Furthermore, the ethanol-induced increase in n-6 and decrease in n-3 elevates the net n-6/n-3 ratio that can be reversed by a diet enriched in n-3 (38, 39, 42)

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This convergence is empirically demonstrated by the concomitant reduction in the activation of caspase-3 and caspase-8, their essential adaptor FADD, and the downstream mediator GSDME