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Potentially severe side effects of Trulicity: Hypoglycemia Gastroparesis (stomach paralysis) Ileus (intestinal blockage) Gallbladder disease Kidney damage Pancreatitis Thyroid tumors (Trulicity carries a boxed warning of thyroid tumors after studies showed an increased risk in animals, but had unclear implications for humans) Allergic reactions Signs and symptoms of serious side effects may include severe abdominal pain, persistent nausea, vomiting, fever, dark urine, or signs of an allergic reaction

The lack of pharmacy options means less flexibility if supply issues arise or if you want to optimize for a specific formulation

"I feel differently about peptides," Ginsberg said

Strength of our study was not needing to use radioactivity or a fluorescence tag to selectively detect modified proteins or peptides (a brief overview of protein detection methods can be found in Table S1)

A "2-week result" in a rat study does not mean a similar timeline applies in humans at 2 weeks (Sikiric et al., 2018)

JAMA Pediatr 2014;168:7218