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Inhibition or depletion of GPX4 utilizing the chemical inhibitor RSL3 or specific siRNA resulted in lipid peroxide accumulation, leading to ferroptosis in H9C2 cells [87]

Product Name: 5-Amino-1-Methylquinolinium (5-Amino-1MQ)

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doi:10.1095/biolreprod.115.130658

Yu et al., 2012)

Excessive ROS production amplifies the recruitment of proinflammatory cytokines, thereby inducing inflammation, oxidative stress, and lipid peroxidation