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While early data show improved persistence, only a minority of patients remain on therapy beyond two years

.,WitykM,DowgiaoGornowiczN,FeszakIBobowiczMFluorescence use in minimally invasive metabolic and bariatric surgery A systematic review of the literature.2023;408(1)

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Distributed under the brand names Geref and Geref Diagnostic, it gained FDA approval in 1997 as a treatment for growth hormone deficiency but was discontinued in 2008 not out of concern for safety or lack of efficacy, but because of manufacturing difficulties.2 3 Yet it remains available in compounded form with a prescription from a licensed healthcare provider

However, the mechanisms underlying LOsG-induced prediabetes remain to be revealed

The researchers didnt dive into why GLP-1s may have this impactthey just found a link