N Engl J Med 377(13):12281239
To listen to my conversation with registered dietitian Jen Cholewka RD, on this topic, check out our episode, "GLP-1s and Nutrition Counseling" on Primary Care Reviews and Perspectives
Importantly, these medications carry boxed warnings for medullary thyroid carcinoma risk and are contraindicated in patients with personal or family history of MEN2 or medullary thyroid carcinoma
The combination drug delayed the rise in A1C to above 7% by a whopping 26 months, compared to metformin alone (62 months, versus 36 months)
Summary of GLP-1 Mechanism: Stimulates insulin release , lowering blood sugar levels
Keep the medication out of the sight and reach of children and do not use it if it has passed the expiry date printed on the packaging