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Similar to NNMT overexpression, MNA-treated hepatocytes show a dose-dependent increase in glucose production, Sirt1 protein expression, G6pc mRNA expression, and Pck1 mRNA expression compared to controls and these changes caused by MNA treatment can be abolished by Sirt1 knockdown [14]

Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene

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