As weve discussed, semaglutide and similar drugs can modulate gut motility in ways that sometimes align favourably with IBS (e.g
Diabetologia 61 , 17241733 (2018)
The most commonly reported side effects were mild to moderate gastrointestinal issues, such as nausea, vomiting, diarrhoea, and constipation, which tended to occur during the higher dose period
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This titration period is necessary to acclimate the body to semaglutide without overwhelming side effects
[DOI] [PMC free article] [PubMed] [Google Scholar] Huang, J