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The secretory proteins were verified using the bulk RNA-seq data (GSE49036, GSE20164) of the GEO database

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The anti-thyroid effect of L-carnitine is based on its ability to inhibit thyroid hormone entry into the nucleus of hepatocytes, neurons, and fibroblasts (186, 210)

For example, LPS from Gram-negative bacterial cell membranes can be bound by CD14 in the presence of LPS-binding protein, which together with MD-2 interacts with TLR4

Furthermore, comparative investigations help support organized research methodologies and repeatable laboratory workflows