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Investigators measured the effects on weight, as well as blood sugar levels, blood pressure, cholesterol levels, and C-reactive protein, which may indicate heart disease risk

That limitation has shaped how insulin is manufactured, stored, transported, and delivered for decades

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Response: We appreciate this comment regarding the use of composite adherence measures or patient-reported outcome process measures (PRO-PM) linked measures to better capture the value of guideline-directed medical therapy in practice

Its currently being explored for its potential in supporting fat loss, muscle preservation, metabolic health, and longevity