When Selectivity Matters Most: The selective action of AOD-9604 is particularly valuable for individuals with insulin resistance, pre-diabetes, or type 2 diabetes who cannot tolerate glucose elevation, those with personal or family history of cancer who wish to avoid IGF-1 elevation, people seeking pure fat loss without muscle gain or other body composition changes, athletes who need fat loss without anabolic effects or hormonal changes that might affect testing, individuals on complex medication regimens where growth hormones effects would require dose adjustments, and those who prefer targeted interventions over systemic hormonal therapy
People with high stress levels, smokers, frequent travelers, or those exposed to pollution may also benefit
Unlike older GH secretagogues, Ipamorelin offers a clean, targeted stimulation of growth hormone with minimal risk of cortisol or prolactin spikes
All authors have read and agreed to the published version of the manuscript
Patients with liver disease, kidney dysfunction, or those taking immunosuppressant medications should undergo provider evaluation before beginning supplementation
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