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Research protocols typically start with lower concentrations (2.5-5 mg/mL) to allow for more precise measurement of small doses using standard insulin syringes

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According to a study , dose escalation helps reduce side effects like nausea and improves long-term tolerability

doi: 10.2337/db10-1332 56 ElliottRMMorganLMTredgerJADeaconSWrightJMarksV

GLP-2-mediated increases in IGF-1 activates the IGF-1 receptor on intestinal epithelial cells to stimulate proliferation (Rowland et al., 2011)

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