However, despite its efficacy, pioglitazone raises some concerns about moderate weight gain (especially in subcutaneous rather than visceral fat), fluid retention, and potential long-term safety issues, warranting careful patient selection and monitoring (American Diabetes Association Professional Practice Committee for Diabetes*, 2025[2])
Anticancer mechanisms of metformin: a review of the current evidence
Ricardo Correa, MD, EdD, the director of the University of Arizona endocrinology fellowship, told MedPage Today in 2022 that compounders are probably using the same active pharmacological part [semaglutide], but when you combine things and you add different excipients, the effectiveness if you dont measure that in a randomized controlled trial will not be the same. He added that not knowing exactly what the formulation contains makes prescribing too risky for him and the patient: Youre treating 100 patients and all of them have been doing fine with a compound medication you recommend
Carnitine supplement intervention and sample collection in the healthy study cohort A total of 56 healthy volunteers, comprising 33 omnivores and 23 vegetarians, were recruited to receive 500 mg of oral supplementation of carnitine fumarate (GNC) daily (equals to 23-fold of carnitine obtained from regular diet) for 1 month
More rarely, these medications may lead to more serious conditions like pancreatitis
Immune attack: the role of inflammation in Alzheimer disease