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Intraperitoneal injections having doses of 1015 mg/kg/day for two weeks in people exhibit features analogous to those observed in animal models [31]

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Skeletal muscle membrane preparation Wild-type RyR1 was purified from rabbit skeletal muscle (purchased from Pel-Freeze Biologicals), and R615C RyR1 was purified from muscle from pigs homozygous for this mutant (purchased from Boyle Farms, Moorehead, Iowa) as described before 38

Indianapolis: Eli Lilly (2026)