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The PfGrx C88S -catalyzed deglutathionylation of monothiol roGFP2 C208S (SSG) is therefore two orders of magnitudes faster than the glutathionylation of roGFP2 C208S (SH) by PfGrx C88S (SSG) (Table 1) corresponding to the strongly shifted equilibrium towards glutathionylated PfGrx C88S and reduced roGFP2 C208S in the redox mobility shift assays (Fig

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BPC-157 appears to work within normal regulatory frameworks rather than overriding them

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In these sequential ATP requiring reactions, the first reaction is rate-limiting and the activity of the GCL is elaborately regulated by intracellular GSH level to maintain GSH homeostasis

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