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A peptide that previously dissolved easily but now requires extensive mixing may have undergone structural changes

Constipation affects a significant portion of people on GLP-1 medications

This is the part that has to stay clear

A particular alteration involves lysosomal dysfunction, which hinders the degradation of structurally damaged mitochondria, leading to cellular toxicity (McGill Percy et al., 2025)

This was followed up by extensive studies by Turton et al