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These rats reacted to a sound that signaled sugar was on the way, in a similar manner to a different sound signaling opioids were on the way

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Hydration becomes particularly important, as reduced appetite may inadvertently decrease fluid intake

Then, the response of the system to growth factors like vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), epidermal growth factor (EGF) and fibroblast growth factor (FGF) was evaluated, to both assess the pro-angiogenic effect and the absence of undesired off-target effect