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Interestingly, although KDS2010 did not reduce elevated astrocytic putrescine levels in PTSD-like mice, suggesting that it does not suppress upstream sources of putrescine synthesis, the restoration of MAOB-dependent GABA homeostasis by KDS2010 may still be sufficient to achieve behavioral recovery (Supplementary Fig

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The advanced lipoxidation end-product malondialdehyde-lysine in aging and longevity

doi: 10.1111/ene.15040 60 MandalSBarnettJBrillSEBrownJSDennenyEKHareSSet al

However, clinical evidence for the use of these drugs in OA is still lacking, so further clinical studies are still needed to investigate