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The PfGrx C88S -catalyzed deglutathionylation of monothiol roGFP2 C208S (SSG) is therefore two orders of magnitudes faster than the glutathionylation of roGFP2 C208S (SH) by PfGrx C88S (SSG) (Table 1) corresponding to the strongly shifted equilibrium towards glutathionylated PfGrx C88S and reduced roGFP2 C208S in the redox mobility shift assays (Fig

Cancer 151, 15351541

Research in animal models shows activity at approximately 0.5mcg/kg, though human protocols typically use standardized doses in the 1-3mg range regardless of body weight

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