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Data extraction focused on the study design, population characteristics, IF protocols, and reported outcomes

Among the 50 generated conformations, the optimal docking result was selected based on Gibbs free energy, and further downstream analysis was focused on this highly ranked conformation

So far, the triple rifabutin regimen has been a saving treatment after many failures (Pellicano et al

Oxidative stress activates NUPR1 by both ER stress (METH [79] and H2O2 [80]) and non-ER stress pathways, NUPR1 regulates ferroptosis via iron metabolism, ROS homeostasis, and the GSH/GPX4 pathway [81, 82]

It was also shown that renal transport proteins that facilitate the urinary excretion of OTA, as well as multidrug resistance (MDR) proteins, were down-regulated [73]

& Rost, J