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If this drug truly improves liver inflammation and fibrosis markers while driving weight loss, thats where it could carve out a real niche. Kristin Kuminski, a registered dietitian nutritionist with The RX Index, who wasnt involved in the trial, called the results significant, placing survodutide at a similar level of efficacy to tirzepatide

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The osteoporotic group showed an increase in GSK3 expression by 2.4-fold versus the control group