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This complexity and the broad spectrum of symptoms make managing and treating long COVID particularly challenging, underscoring the need for innovative approaches and therapies

doi: 10.1038/s41467-023-36519-8 271 ParkJ.LeeK.KimK.YiS

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However, persistent ERS causes lysosomal acidification defects or impaired autophagosome-lysosome fusion, resulting in undegraded autophagosome accumulation, free fatty acid/ROS (OH) release, and necroptosis activation [214]

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