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As multiple studies now show an impact of APOE on brain bioenergetics, which occurs prior to the onset of significant AD pathologies ( Materials and methods Animal models In these studies, APOE-TR mice were housed in groups of up to four under standard laboratory conditions at 23 1C, 50 5% humidity, with a 12-h light/dark cycle and access to food and water ad libitum

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[DOI] [PubMed] [Google Scholar] 99.Wang T, Suzuki K, Kakisaka K, Onodera M, Sawara K, Takikawa Y

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