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To better understand this relationship, future studies should compare AD mice models with disrupted gut microbiomes to those with healthy microbiomes during exercise interventions ( 2.1.5.6 Sleep Sleep and circadian rhythm disturbances are among the hallmark features associated with AD (Musiek et al., 2015)

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Two types of pigment changes can occur: Hyperpigmentation: Darkening of the skin post-treatment, usually temporary but still frustrating

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