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MCC950, a potent inhibitor of the NLRP3 inflammasome, significantly reduces levels of IL-1 and IL-18 in brain tissue and attenuates neutrophil infiltration in mouse models of ischemic stroke (222)

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There are significant inter-ethnic differences in the polymorphism frequency, but it is unclear whether these result in a clinically relevant phenotype (see Table 2 in the supplementary data for a summary of the evidence) [37]

Glutathione is a crucial antioxidant present in every cell in the body

All kinds of things can impact glutathione levels, including time of day, natural aging and exposure to ingested and chemical toxins not to mention constantly generated free radicals

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