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doi: 10.1038/cddis.2014.473

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Who should avoid IGF-1 LR3 Certain individuals should not use IGF-1 LR3 under any circumstances: Absolute Contraindications : Active cancer or history of hormone-sensitive tumors Severe diabetes or uncontrolled blood sugar Pregnancy or nursing mothers History of organ enlargement Active blood clotting disorders Relative Contraindications (may require specialty medical clearance): History of diabetes Cardiovascular conditions Autoimmune disorders Kidney or liver dysfunction History of growth disorders Before starting IGF-1 LR3, comprehensive health screening is essential

Statistical analyses revealed significant interactions between treatment and time for the evaluated vitamins and minerals, indicating differential effects between the two supplements

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