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Researchers study NAD+ in the context of mitochondrial metabolism, oxidative stress models, and enzyme systems such as sirtuins and PARPs

JAMA , 295(17):2003-2017

Gastrointestinal side effects, affecting up to 50% of GLP-1 users, significantly reduce treatment adherence

But the primary concern is the risk of ochronosis, a rare but challenging condition where long-term overuse paradoxically causes darkening of the skin, says Francesa Lewis, MD, a board-certified dermatologist in Delray Beach, Florida

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He said: "Talking to colleagues, they tell me that lots of friends are using this