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10.1038/ki.2015.162 6 AxelssonJ.BergstenA.QureshiA

Nutrients 16 (23), 4068

Subtypes of group II (mGluR2, mGluR3) and group III (mGluR4, mGluR6, mGluR7, and mGluR8) are coupled with Gi/Go to activate MAP kinase and PI-3-kinase pathways and negatively regulate adenylate cyclase (Iacovelli et al., 2010

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In contrast, in the ELIXA trial (once-daily lixisenatide) [29], neither an increase nor a decrease in MACE and the individual component CV events was observed during the follow-up duration (median 2.1 years)

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