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Nevertheless, a pilot study in patients with advanced hepatocellular carcinoma resulted in dose-limiting toxicities and no effects on progression, questioning its efficacy [99]
According to FDA prescribing information, approximately 6% of patients receiving Zepbound discontinued treatment due to adverse reactions compared to 2-3% receiving placebo, with gastrointestinal events being the most common reasons for discontinuation
10.1016/j.devcel.2009.06.016 Dev Cell
Results typically begin within 2472 hours, improving steadily over several days
Increased serum transferrin receptor concentrations in Friedreich ataxia
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