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First, free fatty acids in the cellular cytoplasm are activated by binding to Coenzyme A (CoA), forming a complex called long-chain acyl-CoA

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In this study, mice with specific deletion or overexpression of PRMT1 in tubular epithelial cells were developed, and a CaOx crystal-induced kidney injury mouse model was established

In 2023, the United States Food and Drug Administration (FDA) approved the highest number of new drugs in history (61), marking a record year in pharmaceutical development