Concurrent exercise training: do opposites distract
The hypothalamic-pituitary-gonadal (HPG) axis in men regulates male reproductive function and is comprised of hormone-producing glands in the brain and their target organ, the testes
J Clin Endocrinol Metab 68:276282 [DOI] [PubMed] [Google Scholar] Falutz J, Allas S, Blot K, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S 2007 Metabolic effects of a growth hormone-releasing factor in patients with HIV
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Patients who understand that the GH-IGF-1 cycle operates on a 4 to 8 week minimum timeline, and that cumulative results build over 3 to 6 months of consistent protocol adherence, are the ones who complete a full cycle and achieve meaningful body composition change
This "energy sink" literally starves the brain, heart, and skeletal muscles of energy, directly causing the hallmark symptom of post-exertional malaise (PEM) and the severe exercise intolerance seen in these conditions