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Eosinophilic Esophagitis Adults and Pediatric Subjects 12 Years of Age and Older with EoE A total of 239 adult and pediatric subjects 12 years of age and older, weighing at least 40 kg, with eosinophilic esophagitis (EoE) were evaluated in a randomized, double-blind, parallel-group, multicenter, placebo-controlled trial, including two 24-week treatment periods (Study EoE-1 Parts A and B) and received either DUPIXENT 300 mg QW or placebo [see Clinical Studies (14.4)]

More extensive, high-quality research is necessary

The combination itself is not FDA-approved

Scholkopf, B

In one embodiment, the buffer concentration is about 1.0 M to about 0.07 M

Levocarnitine clears the acyl-CoA compound by formation of acylcarnitine, which is quickly excreted