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Duration of use : The optimal duration of DSIP supplementation varies among individuals and depends on the desired outcomes

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doi: 10.1016/j.phrs.2016.08.034 152 KawamotoYKondoHHasegawaMKurimotoCIshiiYKatoCet al

2 The native hormone has a serious pharmaceutical liability: it is prone to aggregation into amyloid fibrils and has a plasma half-life measured in minutes, which is why the first amylin-based drug, pramlintide, had to be injected before every major meal