Consultado el 22 de diciembre de 2025: Semaglituda semanal en adultos con sobrepeso u obesidad, The New England Journal of Medicine
Given the relatively smaller reduction in body weight (9.4%) in the SELECT trial compared to previous RCTs: 14.9% in STEP1 (BMI 37.86.7 kg/m 2 ) [16] and 13.2% STEP6 (BMI 31.9 kg/m 2 ) [49], pleiotropic effects of semaglutide may contribute to the overall CV risk reduction [25,37]
Standard-dose protocols are usually the better fit when the patients primary goal is significant weight reduction and they are comfortable with a more traditional titration plan
They ought not to take the place of a healthy diet and consistent exercise, though
This release contains forward-looking information about, among other topics, Pfizers plans and pipeline of investigational products, including Pfizers plans for continued development of its oral GIPR antagonist candidate and other earlier obesity programs and their potential benefits, that involves substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements
If your thyroid is normal, taking thyroid hormone wont produce meaningful weight loss and can be dangerous, raising the risk of heart rhythm problems and bone loss