A small pilot study investigated the effect of NAC on pathological gambling
The answer depends on the patients diagnosis, goals, risk factors, medication history, sports rules, available evidence, and whether a medically supervised plan is appropriate

How Pain Medications May Reinforce Nervous System Sensitivity Several commonly used pain medications influence nervous system signaling in ways that may unintentionally reinforce pain over time: Opioids can increase pain sensitivity through opioid-induced hyperalgesia Corticosteroids alter stress-hormone signaling and sleep architecture NSAIDs may impair tissue repair, prolonging nociceptive input Acetaminophen reduces antioxidant capacity needed for neuronal resilience When combined with chronic stress, poor sleep, nutrient depletion, or unresolved inflammation, the nervous system may lose its ability to turn pain off. When Pain Becomes a Conditioned Neurologic Response Over time, pain can become conditioned linked not only to tissue injury, but also to: Movement patterns Emotional stress Previous flare experiences Sleep disruption At this stage, pain is maintained by neural patterning rather than active structural damage
For the most part, you can see that these 2 areas overlay
Neurological Health : Emerging research suggests that glutathione may play a protective role in neurological health
1a, b) binds to double-stranded telomeric repeats and mediates telomere protection, replication and extension 4,14