Their half-lives are 13 hours (LIRA) and 7 days (SEMA), allowing for daily and weekly subcutaneous administration, respectively, thanks to the structural modifications introduced.5,10 Effects on obesity and glycaemic control Both LIRA 3 mg and SEMA 2.4 mg have demonstrated a strong appetite-suppressing and satiety-promoting effect, as well as a delaying effect on gastric emptying.11,12 The SCALE programme highlighted the efficacy of LIRA 3 mg in reducing body weight and waist circumference13 and confirmed a reduction in HbA1c levels in individuals with diabetes, along with a decreased progression from prediabetes to diabetes after three years of treatment14 (Table 1)
The TGA and its partners did not find a direct, causal link between taking a drug like Ozempic and experiencing suicidal or self-harm tendencies
The Role of GLP-1 in Longevity: Optimizing Health through Nutrition, Fitness, and Mindfulness In the quest for a healthier, longer life, scientists and fitness experts have been paying increasing attention to how our bodies regulate hunger, blood sugar, and energy balance
PMID: 40306836, DOI: 10.1016/j.jacc.2025.03.527
Including my good frien
The study also found that non-invasive blood tests and imaging measures reflected treatment-related improvements more clearly than liver biopsies
