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Data were expressed as mean standard error of the mean (SEM), and p values were calculated using two-tailed Students t-test for pairwise comparison of variables and one-way or two-way analyses of variance (ANOVA) for multiple comparison of variables

Age, sex, and baseline BMI also influence stone risk

Peptide therapy is a type of hormone replacement therapy (HRT) that uses natural or synthetic peptides to replace hormones that our bodies naturally produce

However, the mechanisms may vary between different drug classes

penetration-enhanced preparations (including palmitoylated versions such as Pal-GHK) are needed for meaningful dermal delivery Injectable advantages: bypasses the skin barrier entirely, delivers GHK-Cu systemically, and can be combined in the same protocol as BPC-157 and TB-500 for comprehensive wound care The distinction between topical and injectable GHK-Cu is clinically important and is not simply a matter of convenience