Furthermore, the literature suggests that especially in regions without a strong cycling culture, local living will be mostly constricted by what is achieved on foot offering a justification for its walkability focus
Alternative targets in TED include IL-17a (blocked by the IgG1s secukinumab (Cosentyx) and vunakizumab (NCT04737330, NCT05394857)), the IL-11 receptor (NCT05331300), the IL-6 receptor (NCT05331300), and vascular endothelial growth factor (NCT04311606)
J Pharmacol Exp Ther 2011;339:35-44
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