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Although patent 780 specifically claims the method of treating diabetes mellitus, it also discloses how the compounds, including tirzepatide, can be used to treat other indications, including obesity and increasing bone strength

5 In 2021, there were 529 million people of all ages in worldwide living with diabetes, and the global age-standardized prevalence is 6.1%, which increased by 90.5% from 3.2% in 1990, and is expected to reach 9.8%, affecting 13.1 billion people

Reference: Baar MP et al

The SLC22A13 encoded transporter is also involved in high affinity nicotinic acid exchange in the kidneys

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10.1016/S0140-6736(08)61246-5 44 GaultV