Y.HuangR.ZhouC.et al (2024)
Erythrocyte ChE activity was reduced by approximately 35% compared with pre- and post-exposure levels
The SL, RL, FW and DW are important parameters for the classification of tolerance 47
In addition, some polyphenols can enhance the anti-tumour effect while antagonizing ototoxicity.Although polyphenols show good application prospects in the prevention and treatment of cisplatin ototoxicity, there are still some problems that need to be solved, such as the low bioavailability of polyphenols, the mechanism of action has not yet been fully elucidated, the optimal dosing regimen has not yet been determined, whether there is any superimposed effect of combining the various types of polyphenols, and whether the oral polyphenols can exert an otoprotective effect through the regulation of the intestinal flora through the intestinal-auricular axis.This study provides new insights into polyphenols as potential drug candidates for CIO by summarising the cytotoxic mechanisms of cisplatin and the mechanism of action of polyphenols targeting these mechanisms in order to retard the progression of CIO
Selank for anxiety and neurasthenia
This article explores the best injection sites for GHK-Cu peptide therapy , providing clear guidance for those considering or administering this treatment
