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Serine and glycine are needed for cysteine synthesis in one-carbon metabolism, and serine-derived glycine is preferentially used by cancer cells over exogenous glycine
Methods: We implemented siRNA and adenovirus-mediated Ybx1 overexpression in primary human and mouse hepatocytes, as well as continuous hepatocytes, to investigate the effect of Ybx1 modulation on PPAR mRNA levels
Additionally, SELENOP expression was most robust in the choroid plexus and regions lining the brain ventricles (Sasuclark et al., 2019), which is in line with the previous studies (Rueli et al., 2015)
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Journal of neurotrauma
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