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Several FDA-approval drugs will be discussed, including liraglutide, semaglutide, tirzepatide, orlistat, and combinations like phentermine/topiramate and bupropion/naltrexone, noting their effectiveness in obesity management [34, 35] (Table 1)

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These findings suggest that targeting accessible receptors in the CVOs of the brain could be a promising therapeutic strategy for the treatment of obesity

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