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Medications are the first-line treatment, with surgery reserved for those who dont respond to medications or cant take them

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However, it is essential to talk with a doctor before taking any new supplement, as they can interact with medications and underlying conditions

10.1016/j.biopsych.2018.11.006 Biol

When evaluating whether semaglutide might be contributing to leg cramps in an individual patient, clinicians must consider the temporal relationship between medication initiation or dose escalation and symptom onset, the presence of alternative explanations, and whether symptoms resolve with dose adjustment or discontinuation