tirzepatide and bowel movements Relieve Constipation While Taking GLP-1s Tirzepatide and Mucus in Stool:

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Kevin Sheng-Kai Ma, DDS, FRSPH, FRSM, international scholar at the Center for Global Health at the Perelman School of Medicine at the University of Pennsylvania and lead author of this study, told Medical News Today that he and his colleagues were not surprised by these findings, as these [obesity and obesity-related issues] are indications for GLP-1RA that have been approved in recent years. That said, clinicians are encouraged to monitor and continue assessing patients receiving GLP-1RA [drugs], he advised

Patients might experience severe nausea, vomiting, or constipation that impairs quality of life or medication adherence

They are typically transient and do not require stopping the protocol